Access and affordability of extemporaneously compounded essential medicines in some tertiary health facilities in Nigeria

Main Article Content

Dauda A. Dangiwa
Dachen D. Yenwul
Emmanuel A. Adeniji
Maureen Nwafor
Esther M. Hayab
Grace M. Ebuga

Abstract

Background: Some essential medicines are not readily available in the required dosage forms. The availability of extemporaneous preparations is crucial in the provision of medical care to patients, especially the geriatrics and paediatrics.


Objectives: The objective of the study was to evaluate the prevalence of extemporaneous compounding of medicines and the factors affecting patients' access to extemporaneously compounded essential medicines in some tertiary hospitals in Nigeria.


Methods: A retrospective survey was carried out at three different tertiary health facilities, Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BHUTH) Jos, and University of Nigeria Teaching Hospital, Enugu. Medicines for oral use compounded from January 2019 to December 2021 were extracted from pharmacy records using a semi-structured questionnaire and the data was analyzed using Microsoft Excel 2013, IBM SPSS version 21.


Results: About 1,140 of the extemporaneous products, were in liquid dosage form made with trituration using crushed tablets. The most frequent preparations were hydroxyurea (34.39 %), Frusemide (8.86%), lamotrigene (7.54 %), phenobarbitone (6.14 %), clonazepam (5.61 %), spironolactone (5.96%). The most compounded therapeutic class was Antihypertensives, anticonvulsants, vitamins/minerals and least was antihistamines. The value for affordability of the compounded medicines in UNTH, JUTH and BhUTH was less than 1.0, which implies
that all the compounded medicines were affordable.


Conclusion: Extemporaneous compounding is a common practice in the health facilities under consideration. Patients' access to these medicines is affected by the price of the preparations. A higher price reduces accessibility.

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How to Cite
Dangiwa, D. A., Yenwul, D. D., Adeniji, E. A., Nwafor, M., Hayab, E. M., & Ebuga, G. M. (2024). Access and affordability of extemporaneously compounded essential medicines in some tertiary health facilities in Nigeria. West African Journal of Pharmacy, 35(2), 11-18. https://doi.org/10.60787/wajp.vol35no2.351
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Author Biography

Dauda A. Dangiwa, Department of clinical pharmacy and pharmacy practice, Faculty of Pharmaceutical Sciences, University of Jos.

Email: daudadangiwa@gmail.com
Telephone: +2348037224113

How to Cite

Dangiwa, D. A., Yenwul, D. D., Adeniji, E. A., Nwafor, M., Hayab, E. M., & Ebuga, G. M. (2024). Access and affordability of extemporaneously compounded essential medicines in some tertiary health facilities in Nigeria. West African Journal of Pharmacy, 35(2), 11-18. https://doi.org/10.60787/wajp.vol35no2.351

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