Compliance of healthcare providers with National treatment guidelines for HIV/AIDS.
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Abstract
Background: Evidence had shown that low compliance with treatment guidelines by healthcare providers may result in incomplete care of patients thereby defeating the aim of HIV disease management and control.
Objectives: This study was conducted to compare the compliance of a site ART treatment team with the National Guidelines' recommendation on criteria for treatment initiation and regimen change among HIV/AIDS experienced patients.
Methods: In a retrospective observational double cohort study, the medical records of all adults HIV/AIDS positive and treatment experienced patients (N=267) whose ART regimen were either substituted or switched between January 2008 and June 2009 were evaluated for the fulfilment of criteria required before treatment initiation and change of therapy.
Results: The level of compliance with guidelines' recomendations for therapy initiation ranged from 0% - 84.3% (mean= 31.4%; median = 23.2%; SD =21.5%) while compliance with guidelines' recommendations for regimen change ranged from 0% - 61.4% (mean= 31.4%; median = 3.8%; SD =21.5%). There was 100% and 89.2% compliance with 'what to start' and 'when to start' respectively.
Conclusions: Majority of the patients were given appropriate ART regimen at the right time based on the guideline recommendations but compliance with guideline's recommendations for therapy change was poor. The extent of compliance with guideline's recommendations is critical to success of HIV/AIDS control programme.
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References
Federal Ministry of Health (2010): National HIV seroprevalence sentinel survey (HSS). Abuja Nigeria 2010
Federal Ministry of Health (2010): National Guideline for HIV and AIDS treatment and care in adolescents and adults. Abuja-Nigeria 2010; pg 7.
National Agency for the Control of AIDS (2012): Global AIDS response- country progress report.
Chamie K, Saigal CS, Lai J, Hanley JM, Setodji CM, Konety BR and Litwin MS (2011) : Compliance with guidelines for patients with bladder cancer: variation in the delivery of care. Cancer. 117(23): 5392–5401.
Suárez-García I, Sobrino-Vegas P, Tejada A, Viciana P, Ribas M, Iribarren J, Díaz Menéndez M, Rivero M, Arazo P, Del Amo J and Moreno S,
(2014): Compliance with national guidelines for HIV treatment and its association with mortality and treatment outcome: a study in a Spanish cohort. HIV medicine (15)2 pg 86-97
DeMasi RA, Graham NM, Tolson JM, Pham SV, Capuano GA, Fisher RL, Shaefer MS, Pakes GE, Sawyerr GA and Eron JJ (2001): Correlation
between self-reported adherence to highly active antiretroviral therapy (HAART) and virologic outcome. Advances in Therapy 18:4 pp 163-173
Rintamaki LS, Davis TC, Skripkauskas S, Bennett CL and Wolf MS (2006): Social stigma concernsand HIV medication adherence. AIDS Patient
Care STDS. 20(5):359-368.
Tran BX, Nguyen LT, Nguyen NH, Hoang QV and Hwang J (2013): Determinants of antiretroviral treatment adherence among HIV/AIDS
patients: a multisite study. Global Health Action 2013, 6: 19570 http://dx.doi.org/10.3402/gha.v6i0.19570
Ekama SO, Herbertson EC, Addeh EJ, GabOkafor CV, Onwujekwe DI, Tayo F and Ezechi OC (2012): Pattern and determinants of antiretroviral drug adherence among Nigerian pregnant women. Journal of Pregnancy, vol. 2 0 1 2 , Article ID851810, 6 pages ,doi:10.1155/2012/851810
Olisah VO, Baiyewu O and Sheikh TL (2010): Adherence to highly active antiretroviral therapy in depressed patients with HIV/AIDS
attending a Nigerian University teaching hospital clinic. African Journal of Psychiatry; 13:275-279
Shittu RO, Issa BA, Olanrewaju GT, Odeigah LO, Sule AG, Musa AS and Aderibigbe SA (2013): Adherence to highly active antiretroviral
therapy, in depressed peoples living with HIV/AIDS in Nigeria, West Africa. Journal of Antivirals and Antiretrovirals 6: 006-012. doi:10.4172/jaa.1000088
Department of Meteorological Services (2010): World Weather Information Services, Abuja 2010.
Federal Ministry of Health Abuja-Nigeria (2007): National Guideline for HIV and AIDS treatment and care in adolescents and adults. pp 32-70, 108-116.
Cotte L, Benet T, Vanhems P, Brochier C, Perpoint T, Ferry T and Chidiac C (2014): The effect of adherence to guidelines for initial antiretroviral therapy on 1-year outcomes: a French cohort study. BMC Infectious Diseases 14:596
Donkin L, Christensen H, Naismith SL, Neal B, Hickie IB and Glozier N (2011): A systematic review of the impact of adherence on the effectiveness of e-Therapies. Journal of Medical Internet Research 13(3):e52) doi:10.2196/jmir.1772
Hoffman J, Griensven JV, Colebunders R and Mckellar M (2010): Role of CD4 count in HIV management. Medscape education (http://www.medscape.org/viewarticle/713979) accessed on Feb. 4, 2015.
Hogg RS, Yip B, Chan KJ, Wood E, Craib KJP, O'Shaughnessy MV and Montaner JSG (2001): Rates of disease progression by baseline cd4
cell count and viral load after initiating tripledrug therapy. Journal of the American Medical Association; 286(20):2568-2577.
Mbougua JBT, Laurent C, Kouanfack C, Bourgeois A, Ciaffi L, Calmy A, Gwet H, KoullaShiro S, Ducos J, Mpoudi-Ngolé E, Molinari N and Delaporte E (2010): Hepatotoxicity and effectiveness of a nevirapine-based antiretroviral therapy in HIV-infected patients with or without viral hepatitis B or C infection in Cameroon. BMC Public Health, 10:105
Baylor MS and Johan-Liang R (2004): Hepatotoxicity associated with nevirapine use; JAIDS, 15:35(5) pp 538-539
Evron S, Glezerman M, Harrow E, Sadan O and Ezri T (2004): Human immunodeficiency virus: Anaesthetic and Obstetric considerations.
Anesthetic Analog. 98:503-511
Lai S, Mariotti A, Lai C, Testorio M, Carta M, Innico G, Frassetti N, Russo GE (2013): Nephropathies in HIV-infected patients: an overview. OA Nephrology 1(2):15.
Miles K, Clutterbuck DJ, Seitio O, Sebego M and Riley A (2007): Antiretroviral treatment roll-out in a resource-constrained setting: capitalizing on nursing resources in Botswana; Bulletin of the World Health Organ 85:7.
Monyatsi G, Mullan PC, Phelps BR, Tolle MA, Machine EM, Gennari FF, Makosky J and Anabwani GM (2012): HIV management by nurse prescribers compared with doctors at a paediatric centre in Gaborone, Botswana. South African Medical Journal 102(1):34.
Oluoch T, Kwaro D, Ssempijja V, Katana A, Langat P, Okeyo N, Abu-Hanna A and de Keizer N (2015): Better adherence to preantiretroviral therapy guidelines after implementing an electronic medical record system in rural Kenyan HIV clinics: a multicenter pre–post study. International Journal of Infectious Diseases 33 (2015) 109–113
Williams F and Boren SA (2008): The role of the electronic medical record (EMR) in care delivery development in developing countries:
a systematic review. Informatics in Primary Care 16:139–145.
Fraser HSF, Biodich P, Moodley D, Choi S,Mamlin BW and Szolovits P (2005): Implementing electronic medical record
systems in developing countries. Informatics in Primary Care 14:83–95.
Powsner SM, Wyatt JC and Wright P (1998): Opportunities for and challenges of computerization. The Lancet 352:1617–1622
Rosenbloom ST, Crow AN, Blackford JU and Johnson KB (2007): Cognitive factors influencing perceptions of clinical documentation tools. Journal of Biomedical Informatics 40:106-113